Category Archives: Synaptic Plasticity

Making Memories: The Role of Activity-Dependent CRTC1 in Synapse-to-Nucleus Signaling

How does a memory come to be With so many synapses in a dendritic tree? With umpteen connections betwixt cells, How does a nucleus come to tell When and which genes transcribed will be Sufficient to mediate plasticity? The Martin Lab at UCLA Believes that they have found a way. When transmitter binding allows calcium […]

Forming Functional Synapses

Since the discovery of long-term potentiation by Lomo and Bliss in 1973, neuroscientists have been searching for additional evidence of neuronal change based on experience. The concept of synaptic plasticity – the brain’s ability to change and adapt as a result of incoming information – is not new to the neuroscience field. But now, with […]