Tag Archives: Biomarkers

March 05

The Biochemist's Stone: NAD+

NAD+ (pronounced “N-A-D Plus”) is one of the most fundamental, crucial molecules in metabolism throughout all life on Earth. Life without NAD+ is hard to imagine: it holds irreplaceable roles in nearly every cellular process, from handling oxidative stress, DNA repair, and protein folding through to the generation of cellular energy (ATP). How does one […]

February 06

What’s my (brain) age again?

What does it mean to age? Is it a purely time-based process, with each passing moment bringing our bodies along an invariant trajectory of decline? Or is it a function of our behavior, dependent on our daily activities and the damage inflicted upon ourselves over time? Clearly, there is a bit of truth in each […]

November 15

From symptoms to biology: shifting definitions of Alzheimer’s disease

As a neuroscientist studying Alzheimer’s, I’m reminded of its far-reaching impact each time a barista, cashier, or Lyft driver makes small talk by asking what I do for a living. Unfortunately, this devastating disease needs no introduction. Considering its ubiquity, it’s surprising that a debate broke out recently among leaders in the field over the […]